CITRIX

CITRIX "C" DELIVERS VITAMIN C STABILITY

Vitamin C is a powerful antioxidant that may help neutralize the damaging effects of free radicals, the unstable chemicals that are a result of air pollution, smoking, stress and sunlight.

Studies suggest that Vitamin C has the potential to stimulate the growth of collagen that is important in maintaining healthy skin elasticity and texture.

Why Citrix Utilizes L-Ascorbic Acid
Vitamin C in the form of L- Ascorbic Acid is the chemical form of ascorbic acid that can be effectively utilized by the body.

How the Citrix Patented Polymer Matrix Technology Delivers
The unique polymer matrix technology provides an enhanced means of delivering stabilized L- Ascorbic Acid into the skin.

Why Citrix Delivers L-Ascorbic Acid Concentration of 10% & 15%
Research suggests that L-Ascorbic Acid concentration at these levels are necessary to provide enhanced skin care results.

What are some of the benefits of products in the Citrix System?

• The Citrix professional skin care system of multiple strength vitamin C provides a complete step- treatment program.
  
  
• The easy to use Citrix Antioxidant Cleansing Pads are specially formulated with antioxidants and citrus extracts to gently cleanse and prepare the skin.
  
  
• The rich, emollient Citrix Cream in both 10% and 15% L- Ascorbic Acid concentrations is cosmetically elegant and has been specially formulated to help achieve smoother more radiant looking skin.
  
  
• The lightweight, fast absorbing Citrix Serum 10% L- Ascorbic Acid concentration is cosmetically elegant and has been specially formulated to help achieve improvement in skin texture, tone and overall appearance.
  
  
• Rich, emollient antioxidant eye cream delivers soothing benefits of cucumber and chamomile extracts.
  
  
• Antioxidant eye cream blend delivers liposomal Vitamins A,C,E, and Green Tea Extract in combination with Cl-Q10 to assist in minimizing free-radical induced skin damage.
  
  
• Unique liposomal delivery affords enhanced antioxidant penetration.
  
  
• These cosmetically elegant Citric formulations are non - comedogenic and can easily be incorporated into a patients existing skin care regimen.

What are the beneficial skin care properties for the addition of liposome encapsulated TGF-beta-1 to the Citrix Antioxidant serum formulation?
L-ascorbic acid has been reported to help stimulate collagen production. TGF-beta-1 is documented in the medical literature as a chemical messenger which triggers the cell to repair itself. Encapsulation in a liposome helps it penetrate quickly and deposit where it can signal cellular repair.

How much and what percentage of liposome encapsulated TGF-beta-1 growth factor is contained in the Citrix Serum formulation?
TGF-beta-1 is a very powerful growth factor. It has been added at an effective level for high-end cosmetic formulations.

Why is TGF-beta-1 the optimum growth factor that was chosen for addition to the Citrix formula?
TGF-beta-1 has shown clinical efficacy with regard to cellular renewal and is not the type of growth factor that promotes cellular division or proliferation. Growth factors which trigger proliferation have been associated with tumor growth. TGF-beta-1 has an excellent safety and efficacy record.

How do growth factors work in enhancing texture and tone of the skin?
TGF-beta-1 sends a chemical message to the cell signaling it to begin the repair process. When the cell repairs itself, it will be able to make a better copy of itself when it comes time to divide. TGF-beta-1 is being used to formulate drugs for wound healing and tissue repair by making use of this property.

Are there any irritation or side effect issues to be concerned with in using liposome encapsulated TGF-beta-1 growth factor?
No, TGF-beta-1 was specially selected for its safety and efficacy record. TGF-beta-1 is not an irritant.

How does foundation make-up work with Citrix Serum with growth factor and can a sunscreen be applied on top of the foundation?
Foundation make-up can be applied after the Citrix with growth factor is allowed to dry thoroughly. Regular use of sunscreen is always recommended. The usual order is Citrix the sunscreen then foundation, allowing each to dry before adding the next.

How long do patients need to use the Citrix Serum with TGF-beta-1 before noticing beneficial benefits to the skin?
Beneficial effects can be noticed after a couple of applications. After a couple of weeks, the effects are more dramatic. It is also important to keep in mind the photo-protective effects of the vitamin C. Studies show a reduction in the amount of sunburn cells formed in the skin after UV exposure and a decrease in erythema normally associated with UV exposure.

Are there any product stability concerns with L-ascorbic acid being combined with growth factor TGF-beta-1? Product color changes, smells, breakdown, etc.?
The breakdown by-products of L-ascorbic acid are dark brown in color. If the product were ever to darken to the color of a manila file folder the L-ascorbic acid level would begin to approach about 90% of the label-claimed amount. Our stability studies have shown excellent results and there should not be any significant change in the product thoughout its use cycle.